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Macular Degeneration Research

Collection by WebRN Macular Degeneration

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Macular degeneration research can be observational or interventional. Find out about some of the latest clinical trials for dry and wet macular degeneration that is offering hope to those with this retinal condition. #maculardegenerationresearch

WebRN Macular Degeneration
"The study found that RPE patches transplanted under the macula, or the central part of the retina, remained stable and integrated in vivo for at least three months without serious side effects such as immune attack or light sensitivity. .. the stem cell-derived RPE at least partially took over the function of the original RPE and was able to support the endogenous photoreceptor, which helps with light and water absorption among other functions." #maculardegenerationtreatmentbreakthrough Macular Degeneration Treatment, Study Site, Degenerative Disease, The Retina, Gene Therapy, Eyes Problems, In Vivo, Light Sensitivity

Retinal Cell Transplants to Treat Macular Degeneration

"The study found that RPE patches transplanted under the macula, or the central part of the retina, remained stable and integrated in vivo for at least three months without serious side effects such as immune attack or light sensitivity. .. the stem cell-derived RPE at least partially took over the function of the original RPE and was able to support the endogenous photoreceptor, which helps with light and water absorption among other functions." #maculardegenerationtreatmentbreakthrough

"The objective of this study is to investigate the potential efficacy and safety of vitamin A palmitate dosing in improving dark adaptation in participants with age-related macular degeneration (AMD) and abnormal dark adaptation." #maculardegenerationresearch Investigations, Research, Vitamins, Safety, Study, Age, Search, Security Guard, Studio

Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration

"The objective of this study is to investigate the potential efficacy and safety of vitamin A palmitate dosing in improving dark adaptation in participants with age-related macular degeneration (AMD) and abnormal dark adaptation." #maculardegenerationresearch

"Chavala and his team identified a new method to alter cell identity and reprogram skin cells into retinal cells. ...The result is the creation of rod photoreceptors that mimic in appearance and function the innate rods that normally develop on the outermost layer of the retina." #maculardegenerationresearch Skin Anatomy, The Retina, New Details, Blue Backgrounds, Clipart, Vector Free, Royalty Free Stock Photos, Neon Signs, Creative

Reprogram Skin Cells to Retina Cells

"Chavala and his team identified a new method to alter cell identity and reprogram skin cells into retinal cells. ...The result is the creation of rod photoreceptors that mimic in appearance and function the innate rods that normally develop on the outermost layer of the retina." #maculardegenerationresearch

“The protocol, which prevented blindness in animal models, is the first clinical trial in the U.S. to use replacement tissues from patient-derived induced pluripotent stem cells (iPSC),” said Kapil Bharti, Ph.D., a senior investigator and head of the NEI Ocular and Stem Cell Translational Research Section. #maculardegenerationandstemcells Cure Diabetes, Lasik Eye Surgery, Natural News, Eyes Problems, Nail Fungus, Optometry, Eye Doctor, Tecnologia, Natural Remedies

AMD Research Rescues RPE and Rods and Cones

“The protocol, which prevented blindness in animal models, is the first clinical trial in the U.S. to use replacement tissues from patient-derived induced pluripotent stem cells (iPSC),” said Kapil Bharti, Ph.D., a senior investigator and head of the NEI Ocular and Stem Cell Translational Research Section. #maculardegenerationandstemcells

"One of the antioxidants that is most present in the eyes to fight oxidative stress is glutathione, the defecit of which is linked to several ophthalmologic diseases. The research group of the CEU UCH of Valencia headed by professor Alicia López Castellano and specialized in developing new pharmaceutic means for the administration of medicines ..." #maculardegenerationresearch Gene Expression, Medicine Journal, Cell Membrane, Hip Openers, Chronic Stress, Liver Disease, Important Facts, Alternative Therapies, Fatty Liver

Ocular Device Delivers Antioxidant Glutathione to the Eyes

"One of the antioxidants that is most present in the eyes to fight oxidative stress is glutathione, the defecit of which is linked to several ophthalmologic diseases. The research group of the CEU UCH of Valencia headed by professor Alicia López Castellano and specialized in developing new pharmaceutic means for the administration of medicines ..." #maculardegenerationresearch

"As the CEU UCH researchers explain in the study, glutathione is the most available natural antioxidant in the eyes, and a deficit is linked to pathologies of the retina, the human tissue that consumes the most oxygen: Hence the need to for better protection against oxidative stress via glutathione." #maculardegenerationresearch Gallbladder Attack, Antioxidant Supplements, Alpha Lipoic Acid, Cell Membrane, Oxidative Stress, Anti Aging, Science, Adrenal Health, Gut Health

New ocular device helps administer antioxidant glutathione in the eye

"As the CEU UCH researchers explain in the study, glutathione is the most available natural antioxidant in the eyes, and a deficit is linked to pathologies of the retina, the human tissue that consumes the most oxygen: Hence the need to for better protection against oxidative stress via glutathione." #maculardegenerationresearch

"Researchers found that combining apolipoprotein A-I binding protein (AIBP) with anti-VEGF overcomes anti-VEGF resistance and effectively suppresses CNV. The findings open the possibility of reducing anti-VEGF resistance in patients in the future. The study appears in the journal Communications Biology." #maculardegenerationresearch Best Vegetarian Sandwiches, Eye Chart, Life Magazine, Drugs, Photo Editing, Math, Memes, Blog, Veggie Meals

Combating drug resistance in age-related macular degeneration

"Researchers found that combining apolipoprotein A-I binding protein (AIBP) with anti-VEGF overcomes anti-VEGF resistance and effectively suppresses CNV. The findings open the possibility of reducing anti-VEGF resistance in patients in the future. The study appears in the journal Communications Biology." #maculardegenerationresearch

Adverum Biotechnologies to Present Additional Clinical Data from First Cohort of OPTIC Phase 1 Trial of Intravitreal Gene Therapy to Treat Wet AMD at the American Academy of Ophthalmology 2019 Annual Meeting Macular Degeneration Treatment, Eye Center, Cell Line, The Retina, Gene Therapy, Radiation Therapy, Regenerative Medicine, Light Sensitivity, Dna

Macular Degeneration Research Using Gene Therapy

"“The beauty of our strategy is its simplicity,” said Samarendra Mohanty, Ph.D., Nanoscope founder and corresponding author of a report on the mouse study that appears today in Nature Gene Therapy. “Bipolar cells are downstream from the photoreceptors, so when the MCO1 opsin gene is added to bipolar cells in a retina with nonfunctioning photoreceptors, light sensitivity is restored.”

""By enabling near-infrared light sensitivity, we hope to ultimately restore central vision, so that people with macular degeneration can regain the ability to read and recognize faces," says Botond Roska, Director at IOB, and one of the paper's corresponding authors." #maculardegenerationresearch Gene Therapy, Light Sensitivity, Enabling, Restore, Authors, Faces, People, The Face, People Illustration

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""By enabling near-infrared light sensitivity, we hope to ultimately restore central vision, so that people with macular degeneration can regain the ability to read and recognize faces," says Botond Roska, Director at IOB, and one of the paper's corresponding authors." #maculardegenerationresearch

"Abfero has been working with Dr. Joshua Dunaief, Adele Niessen Professor of Ophthalmology at the University of Pennsylvania’s Scheie Eye Institute and a leading expert on retinal diseases and the role of iron in retinal degeneration. His work, and that of others in the retinal community, have shown that iron overload in the retina can cause retinal degeneration and that retinal free iron worsens disease severity in a variety of disease models." #maculardegeneration Retinal Degeneration, The Retina, Adele, Pennsylvania, Professor, University, Iron, Community, Teacher

Abfero Targeting Excess Iron to Treat AMD, Other Retinal Diseases

"Abfero has been working with Dr. Joshua Dunaief, Adele Niessen Professor of Ophthalmology at the University of Pennsylvania’s Scheie Eye Institute and a leading expert on retinal diseases and the role of iron in retinal degeneration. His work, and that of others in the retinal community, have shown that iron overload in the retina can cause retinal degeneration and that retinal free iron worsens disease severity in a variety of disease models." #maculardegeneration

Vitamin D and Homotaurine Show Potential Benefit for Macular Degeneration Vitamin D, Benefit

Vitamin D and Homotaurine Show Potential Benefit for Macular Degeneration

Discussing the results of a study examining impact of vitamin D and homotaurine supplementation on early to intermediate age-related macular degeneration.

Nano Retina is involved with developing a retinal chip to help restore sight to those with degenerative retinal diseases. Macular Degeneration Treatment, Optic Nerve, Cell Line, Degenerative Disease, The Retina, Gene Therapy, Radiation Therapy, Regenerative Medicine

Retina Implant called Nano Retina

Nano Retina is involved with developing a retinal chip to help restore sight to those with degenerative retinal diseases. #retinaimplant #maculardegenerationresearch

Wet Macular Degeneration Clinical Trials: Gene Therapy to Eye Drops Macular Degeneration Prevention, Science Of Consciousness, Paris Saclay, Mindfulness At Work, Ashkenazi Jews, Human Dna, Cancer, Gene Expression, Gene Therapy

Macular Degeneration Research - Insert New Code

". ..some scientists believe they will soon be able to insert new code into the body’s own genome — the instruction manual “written” on the chromosomes in every cell — to direct the body to build or rebuild healthy eyes long into maturity. #maculardegenerationresearch

Wet Macular Degeneration Clinical Trials: Gene Therapy to Eye Drops Study Site, Study Test, Macular Degeneration Symptoms, The Retina, Gene Therapy, Clinical Research, National Institutes Of Health, Body Systems, Blood Vessels

Wet Macular Degeneration Research - Less Frequent Eye Injections

"“GB-102 has the potential to help patients control their disease by addressing the treatment burden of wet AMD with a single injection every six months ...” said Arshad M. Khanani, M.D., M.A., Managing Partner and Director of Clinical Research, Sierra Eye Associates, and Clinical Associate Professor of Ophthalmology, University of Nevada." #maculardegenerationresearch

"Vitamin improves retinal function through reducing inflammation, reducing the number of activated macrophages, and clearance of amyloid-beta deposition. Observational Study, Vitamin D Deficiency, Bone Health, Research, Health Benefits, Science, Eyes, Risk Factor, Number

Macular Degeneration Research and Vitamin D

"Vitamin D deficiencies have been repeatedly associated with various acute and chronic diseases, including age-related macular degeneration (AMD)...cumulative data from experimental and observational studies suggest that relatively a lower vitamin D status could be a potential risk factor for the development of early and/or late AMD." #maculardegenerationresearch

Illustration of a blood cell turning into an induced pluripotent stem cell and then an RPE cell. Translational Research, Stem Cell Research, Medical Research, Retinal Degeneration, Science Programs, Stem Cell Therapy, Healthy Eyes, Good Manufacturing Practice, National Institutes Of Health

Macular Degeneration Research and Stem Cells

There are several different ways to obtain, develop and utilize stem cells that don't require cells coming from an embryo. These cells are called adult (non-embryonic) stem cells. #maculardegenerationresearch